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Just six decades after Orville and Wilbur Wright launched the aviation age, President Kennedy pronounced a moonshot: fly people to the moon and back. Eight years later, the mission was accomplished. Now, six decades after James Watson and Francis Crick discovered the code of life, it is time to embark on another historic mission: hack the code of life and cure aging.
—

The Palo Alto Longevity Prize (the “Prize”) is a $1 million life science competition dedicated to ending aging. Ours is one of a growing number of initiatives around the world pursuing this goal—the more shots on goal the better. Through an incentive prize, our specific aim is to nurture innovations that end aging by restoring the body’s homeostatic capacity and promoting the extension of a sustained and healthy lifespan.

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There are two prizes available and teams may compete for one or both prizes:

• A 内蒙古新增境外新冠肺炎输入确诊和疑似病例4例-解决网:2021-6-12 · 抗击新冠肺炎)内蒙古新增境外新冠肺炎输入性确诊病例和疑似病例4例中新网呼和浩特3月25日电 (记者张玮)25日凌晨，内蒙古自治区卫生健康委发布消息：2021年3月20日20时至24日22时，内蒙古报告新增境外新冠肺炎输入性病例4例，其中2例 ... will be awarded to the first team to demonstrate that it can restore homeostatic capacity (using heart rate variability as the surrogate measure) of an aging reference mammal to that of a young adult.

• A $500,000 Longevity Demonstration Prize will be awarded to the first Team that meets all the requirements of the Prize Requirements as determined by the Judging Panel in its sole discretion, including extending the mean lifespan of a wild-type mammalian intervention cohort by 50% relative to acceptable published natural history of untreated norms in a statistically significant (p<.05) manner, using a Statistical Model (as defined and approved in the official “Competition Agreement”). The intervention and control cohorts should be age and gender matched and should include an equal number of males and females. If you would like more details on the Prize Requirements please use the contact form at the bottom of this page.

Each team participating in the Prize is responsible for funding 100% of its participation in the Prize including all research and development costs and publishing its work and/or the reproduction of results. To enable a rapid commercial path forward for the innovations, the sponsor of the Prize will be contributing an existing pool of relevant intellectual property to the Prize effort.

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Innovation happens in the most magical ways and often it requires people from outside the field of study to see the challenge with a new perspective. If you are ready to sign up as a team to compete – please fill out an Intent to Participate Application If you have any questions or if you would like to review the Prize rules, please let us know.

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“There is a possibility that the timed switch from a functional ANS to a dysfunctional ANS may be a key underlying mechanism of chronic diseases and aging.”

Frank Longo, M.D. Professor and Chair, Department of Neurology and Neurological Sciences, Stanford University

“The Palo Alto Longevity Prize has the potential to fundamentally impact humankind by unlocking the secrets to longevity and healthy aging.”

Amir Dan Rubin President and CEO Stanford Hospital & Clinics

“The answers we find with this prize could not only teach us how to enhance lifespan but more importantly brain function and human health in general.”

手机浏览国外网站的方法 Chairman, Department of Neurobiology, Stanford University

“Health extension needs to happen sooner rather than later. I, for one, do not want to be part of the last generation that only lived to an average of 80 years.”

Sonia Arrison Author 100 Plus, Associate Founder Singularity University

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Keith Powers Managing Director, Engaged Partners

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Laura Deming Founder, Longevity Fund

“Heart rate variability is a powerful potential biomarker. This prize will attract the best and brightest to take on the full puzzle.”

Nina Kjellson Managing Director, Interwest Ventures

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Steve Herrod Managing Director, General Catalyst Partners

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Incentive prizes work because they attract:

Minds

Prizes attract the best minds to focus on finding solutions to a specific area of innovation. From researchers at universities, to startups, to small teams within larger companies, prizes create a target for innovators to try to solve. Prize purses, advanced market commitments, and the glory of winning helps “pull” innovation in a specific direction. By creating a new playing field, prizes also help pull everyone together toward the common goal.

Media

Everyone loves a competition and everyone loves heroes, especially the media! When crafted and produced well, incentive prizes are a great way to tell stories and to educate the public about the area of discovery. They also provide a wonderful medium to create heroes out of the hard-working teams that make it happen.

Money

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Now is the time to launch this prize, because we have reached the point in science, where we really do have the opportunity to solve aging.
Dr. Doris Taylor
The Palo Alto Prize enables us to attack moonshot problems
Jin Lee
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Doris Taylor
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David Mendelowitz
The race against time is imminent. We need to act now
David Mendelowitz
Every moment of our life is a race against time
Jin Lee
The longer people live and the more productive they are the more they contribute to society
Irving Zucker
We’ve reached a point in science where we really do have the opportunity to solve aging
Doris Taylor
You never change things by fighting the existing reality. To change something, build a new model that makes the existing model obsolete.
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If you keep us in this room long enough, we will solve aging
Dr. Doris Taylor
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We have to reinvent ourselves to make progress
Irving Zucker

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VICTOR DZAU, M.D.

LEONARD GUARENTE, Ph.D.

Director, Glenn Laboratory for the Science of Aging at MIT

Dr. STUART KIM, Ph.D

Professor, Depts. of Developmental Biology and Genetics

Stanford University Medical Center

DAVID SINCLAIR, Ph.D.

Professor, Genetics Dept. Harvard Medical School

JOHN SEDIVY Ph.D.

Brown Faculty, Department of Molecular Biology, Cell Biology, and Biochemistry

KEITH BLACKWELL, M.D, Ph.D.

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Alliance for Aging Research

RUSSEL J. REITER, Ph.D., Dr.H.C.MULT.

Professor of Cell Biology, UT Health Science Center

STEVE JURVETSON

Managing Director, Draper Fisher Jurvetson

JACK HIDARY

Founder, Hidary Foundation

FRANK LONGO, M.D.

Professor and Chair, Department of Neurology and Neurological Sciences, Stanford University

CHARLES CHO, M.D.

Professor of Neurology and Neurosurgery, Stanford University

ERIC VERDIN, M.D.

Senior Investigator, Gladstone Institute of Virology and Immunology Professor, UCSF School of Medicine

KEVIN PERROTT

Executive Director – Mprize, Methuselah Foundation

手机上境外网加速软件 Benefactor of the Palo Alto Longevity Prize Joon is the President of Palo Alto Investors, LLC, founded in 1989 with $1 billion in assets under management invested in healthcare. Board certified in radiology, Dr. Yun served on the clinical staff at Stanford Hospital from 2000-2006. Dr. Yun received his Bachelor of Arts in biology from Harvard University and his Doctor of Medicine from Duke University School of Medicine. He is a contributor to Forbes. 手机翻国外网站教程@DrJoonYun.

SONIA ARRISON

Author, 100 Plus

KEITH POWERS

President, Engaged Partners (Frm. EVP of Strategy, X PRIZE Foundation)

GUY P. NOHRA

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REESE JONES

Associate Founder, Singularity University; Trustee, Santa Fe Institute

FEDERICK J. DOTZLER

Managing Director, De Novo Ventures

NINA KJELLSON

Managing Director, Interwest Ventures

LAURA DEMING

Founder, Longevity Fund

STEVE HERROD

Managing Director, General Catalyst Partners

STEVE VASSALLO

General Partner, Foundation Capital

CAMI SAMUELS

Managing Director, Versant Ventures

GARHENG KONG, M.D., MBA

Managing General Partner, Sofinova Ventures

PATRICK ENRIGHT

Founder and Managing Director, Longitude Capital

JIM GLASHEEN, PH.D.

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ROGER J. QUY, PH.D.

General Partner, Technology Partners

KEVIN STARR

Partner, Third Rock Ventures Patrick-Enright

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Founder and CEO, ExploraMed

KERRY DOLAN

Assistant Managing Editor, Forbes

AMIR RUBIN

President and CEO of Stanford Hospital & Clinic

BARBARA J. NATTERSON-HOROWITZ, M.D.

Professor of Medicine, UCLA Division of Cardiology

DAN MOORE

President and CEO, Cyberonics, Inc.

GRAHAM SPENCER

General Partner, Google Ventures, Trustee, Santa Fe Institute

BOB HARRINGTON, M.D.

Chairman, Department of Medicine, Stanford University

DAVID ARRINGTON

Associate Vice Chancellor, University Relations, UC San Francisco

AUBREY DE GREY, MA, PH.D

Ph.D, Chief Science Officer, SENS Foundation

VALTER LONGO, PH.D.

Director, USC Longevity Institute

JEAN-JACQUES BIENAIME

CEO, Biomarin

BEN BARRES, M.D., PH.D.

Chairman, Department of Neurobiology, Stanford University

FRANK FISCHER

President and CEO, Neuropace, Inc.

JAMES R. DOTY, M.D.

Professor of Neurosurgery, Stanford University Founder and Director of CCARE

ALAN GREENE, MD

Author, Pediatrician, Founding President of the Society of Participatory Medicine

BRIAN KENNEDY,PH.D.

CEO and President, The Buck Institute for Research on Aging

LEIGHTON READ, M.D.

HOYOUNG HUH

Managing Director, Konus Advisory Group

ALBERT CHA

Managing Partner, Vivo Ventures

MICHAEL MCCULLOUGH, M.D.

JENNIFER ALDEN

Director, Digital Content Strategy, Palo Alto Investors

CASPER deCLERQ

Partner, Norwest Venture Partners

CHARLES WARDEN

Managing Director, Versant Ventures

OLEG NODELMAN

Managing Partner, EcoR1 Capital

STACEY CHANG

Director, Healthcare Practice at IDEO

WAYNE B. JONAS, M.D.

President & CEO Samueli Institute

CONRAD YUN

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The Race Against Time (dba The Hero Science Foundation www.herosf.org) is a 501(c)(3) educational non-profit organization (Tax ID: 47-2823482) created to raise public awareness and financial support for basic biomedical research related to increasing our health span and defining the fundamental biological mechanisms that prevent age-related diseases and disabilities.

About the prize sponsor:

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